MOLECULAR PROCESSES STUDIED AT A SINGLE-MOLECULE LEVEL USING DNA ORIGAMI NANOSTRUCTURES AND ATOMIC FORCE MICROSCOPY

Molecular Processes Studied at a Single-Molecule Level Using DNA Origami Nanostructures and Atomic Force Microscopy

DOPHILUS PLUS DNA origami nanostructures allow for the arrangement of different functionalities such as proteins, specific DNA structures, nanoparticles, and various chemical modifications with unprecedented precision.The arranged functional entities can be visualized by atomic force microscopy (AFM) which enables the study of molecular processes a

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Determination of the starting dose in the first-in-human clinical trials with monoclonal antibodies: a systematic review of papers published between 1990 and 2013

Hoon Young Suh,1 Carl C Peck,2 Kyung-Sang Yu,1 Howard Lee1,3 1Department of Clinical Pharmacology and Therapeutics, College of Medicine, Seoul National University Hospital, Seoul, Korea; 2Department of Bioengineering and Therapeutic Sciences, School of Pharmacy, University of California, San Francisco, CA, USA; 3Department of Transdisciplinary Stud

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